Systemic abnormal glycosylation has been proposed to contribute substantially to the ongoing pathophysiology. While this is lifesaving in the neonate, complications persist in treated individuals, and the cause of these, despite early initiation of treatment, and shared GALT genotypes remain poorly understood. The disease is life threatening if left untreated in neonates and the only available treatment option is a long-term galactose restricted diet. The selection of available Italian titles will include ‘ Circeo,” the series produced by Cattleya in collaboration with Vis, Paramount+ and Rai Fiction which retraces the process following double murders in 1975 “14 Days,” a Paramount+ original Italian production, written and directed by Ivan Cotroneo, which tells the story of a couple forced into two weeks of seclusion the “Corpo Libero” series, a co-production by Indigo Film and Network Movie, in co-production with ZDFneo, in collaboration with Rai Fiction and Paramount+, in association with All3Media International Limited: the thriller based on the novel by Ilaria Bernardini.Classical galactosaemia is a rare disorder of carbohydrate metabolism caused by galactose-1-phosphate uridyltransferase (GALT) deficiency (EC 2.7.7.12). Paramount originals available at launch include “ The Offer,” “ Tulsa King” and “ Halo.” Upcoming originals include “ 1883,” Taylor Sheridan’s “ Yellowstone” prequel and “1923,” also from Sheridan, featuring Helen Mirren and Harrison Ford in the next instalment of the “ Yellowstone” origin story. 15 in Italy with some 8,000 hours of content spanning all genres at launch. Streaming Streamer Paramount+ will arrive Sept. She executive produced and starred in Taking the Reins for Hallmark Channel and showcased her acting range in Five More Minutes, which premiered in 2021 during “Miracles of Christmas” on Hallmark Movies & Mysteries. DeLoach also starred as the lead in the Hallmark Movies & Mysteries original Two Turtle Doves opposite Michael Rady. She also developed, executive produced and starred in Reunited at Christmas, as well as co-wrote Christmas for Keeps with her writing partner Megan McNulty, which aired during “Miracles of Christmas” on Hallmark Movies & Mysteries. Hallmark Channel viewers should recognize DeLoach from her starring roles in such original movies as The Perfect Catch, Christmas Land, A Dream of Christmas, Truly, Madly, Sweetly and Love Takes Flight, which premiered as a Hallmark Hall of Fame presentation. Exclusive: Hallmark Media wants to stay in the Nikki DeLoach business: It has signed the Five More Minutes actress to an exclusive, multi-picture overall deal.
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